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Herpes Simplex Virus (HSV) Placental Culture

Published: August 9, 2026Updated: August 16, 2026

This test checks for the presence of the herpes simplex virus (HSV) in placental tissue, which may help identify if the virus was transmitted during pregnancy.

Quick summary

["Placental HSV culture helps assess potential infection risks during pregnancy."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
35425-8
Short code
HSV Placenta Cult
Synonyms
HSV Placenta Cult
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
organism-specific-culture
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may recommend this test if there is a concern about HSV infection during pregnancy. This could happen if you have symptoms of HSV, have been exposed to the virus, or if you have a history of recurrent infections. The test helps ensure the health of both you and your baby.

What Does the Test Involve?

A small sample of placental tissue is collected during delivery. This sample is then sent to a lab to grow HSV cultures. The lab will examine the tissue for signs of the virus over time.

What Are the Possible Results?

If HSV is detected in the placental tissue, it may indicate that the virus was present during pregnancy. If no HSV is found, it suggests the placenta was not infected at the time of testing. Results can influence further prenatal care and delivery planning.

What Does This Test Tell You About Your Baby?

While this test focuses on placental tissue, it does not directly assess whether your baby was infected. However, identifying HSV in the placenta can help guide decisions about monitoring your baby’s health post-birth and may influence delivery plans to minimize exposure risk.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Positive results may indicate a higher risk of neonatal HSV infection, which can be serious. Healthcare providers will use these findings alongside other clinical assessments to tailor care, such as monitoring newborns closely or considering specific delivery precautions. Negative results suggest no active HSV infection in the placenta but do not guarantee the baby is free from HSV entirely.

Short name

HSV Placental Culture

Frequently asked questions

What does a positive result mean for my baby’s health?
A positive result means the placenta tested positive for HSV, which could increase the risk of the virus being passed to your baby. Your healthcare team will work with you to monitor your baby closely after birth and may recommend additional precautions or tests.
Can this test detect HSV in my baby’s blood?
No, this test specifically examines placental tissue. To check for HSV in your baby, a separate blood test (often called HSV PCR) is typically performed shortly after birth.
Will I need to take any special precautions if this test is positive?
If the placental culture is positive, your healthcare provider may recommend additional monitoring of your baby, such as frequent check-ups or specific tests. They may also discuss delivery plans to minimize exposure risk, like avoiding vaginal delivery in some cases.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy