Herpes Simplex Virus (HSV) Skin Culture

Why Is This Test Done?

Your healthcare provider may order this test if you have a rash or lesion on your skin that looks like herpes, especially if it’s painful, recurrent, or spreading. It’s also used to diagnose HSV infections in areas not typically affected by cold sores (like the eyes or genital region).

How Is the Test Performed?

A small sample of your skin lesion is collected using a swab or by scraping the affected area. The sample is then sent to a lab where it’s placed on a special culture medium to grow HSV, if present. Results can take several days to a week or more, depending on the lab’s process.

What Does the Test Result Mean?

A positive result means HSV was grown from your skin sample, confirming an HSV infection. A negative result means no HSV was detected in the sample, but other causes of the rash could still be possible. Follow-up testing or evaluation may be needed if symptoms persist.

What Are the Possible Side Effects?

There are usually no side effects from the skin swab or scraping, but you may experience mild discomfort or slight redness at the site. If you’re allergic to any lab supplies (like swabs or culture media), let your provider know before the test.