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Herpes Simplex Virus (HSV) Type 1/2 Antibody, Qualitative (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test detects antibodies to herpes simplex virus (HSV), which can help identify past or current infection with either HSV-1 or HSV-2.

Quick summary

["This test helps determine if you’ve been exposed to herpes simplex virus, which can cause cold sores or genital herpes."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
35434-0
Short code
HSV Wnd Cult
Synonyms
HSV Wnd Cult
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
organism-specific-culture
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test looks for antibodies—proteins your immune system produces in response to HSV infection. If antibodies are present, it suggests you’ve been exposed to HSV at some point, even if you don’t currently have symptoms.

Why It’s Done

Doctors may order this test if you have symptoms like sores, pain, or unusual rashes that could be related to HSV, or if you’re at higher risk for infection (e.g., sexually active individuals, pregnant women, or those with weakened immune systems).

What to Expect Before the Test

No special preparation is needed. You’ll provide a blood sample, usually drawn from your arm. The test is quick and typically done in a lab setting.

What the Results Mean

A positive result means antibodies to HSV are detected, indicating past exposure. A negative result means no detectable antibodies were found, but this doesn’t rule out current infection—other tests may be needed for confirmation.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HSV Antibody Screen (Qualitative)

Frequently asked questions

Does this test show if I currently have herpes?
No, this qualitative antibody test detects past exposure. To determine if you have an active infection, your doctor may recommend additional testing.
What does a positive result mean?
A positive result means your immune system has recognized HSV at some point, but it doesn’t specify which type (HSV-1 or HSV-2) or whether you’re currently infected.
Can I get this test at home?
No, this test requires a blood sample collected by a healthcare professional in a clinical setting.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy