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Serum/plasma concentration of total protein by nephelometry

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of protein in your blood serum or plasma, which helps assess overall protein levels in your body.

Quick summary

["Total protein levels can indicate hydration, liver function, or potential protein loss conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
73352-7
Short code
HTCZ ind plt IgM SerPl Ql FC
Synonyms
HTCZ ind plt IgM SerPl Ql FC
Category
hematology
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
flow-cytometry
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Doctors may order this test to evaluate conditions like malnutrition, kidney disease, liver problems, or to monitor protein loss due to conditions like burns, kidney failure, or certain cancers. It can also help check hydration status or diagnose conditions affecting protein synthesis or breakdown.

What Does the Result Mean?

Results are not provided with specific numeric ranges here, as they vary by lab and health status. High or low protein levels may signal underlying health issues that need further medical evaluation.

Common Conditions Affecting Protein Levels

Abnormally high protein levels might suggest dehydration, multiple myeloma, or severe infections. Low protein levels could indicate liver disease, kidney problems, or malnutrition. Always discuss results with your healthcare provider.

Sample Collection and Preparation

A blood sample is drawn from a vein in your arm. You may feel a slight pinch, but it usually doesn’t cause discomfort. The blood is processed to separate serum or plasma for testing.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Total Protein

Frequently asked questions

What might cause abnormal results?
Abnormal results could be due to conditions like kidney disease, liver disease, dehydration, malnutrition, or certain cancers. It’s important to discuss symptoms and medical history with your doctor to understand potential causes.
How often should I get this test?
Your doctor will determine the frequency based on your health needs, symptoms, or ongoing conditions. Regular monitoring may be recommended if you have chronic health issues.
Can I eat or drink before this test?
Typically, fasting is not required for this test, but follow your healthcare provider’s instructions. Avoid alcohol for 24 hours before testing if advised.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy