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Immunoassay for Antibodies to Hepatitis B Virus Surface Antigen (IgG)

Published: August 9, 2026Updated: August 16, 2026

This test measures your body’s immune response to the hepatitis B virus by detecting hepatitis B surface antibody (anti-HBs) in your blood. It helps determine if you’ve been vaccinated or previously infected with hepatitis B.

Quick summary

["Checks immunity to hepatitis B, whether from vaccination or past infection."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
11260-7
Short code
HTLV I Ab Ser Ql IA
Synonyms
HTLV I Ab Ser Ql IA
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you’re at risk for hepatitis B (e.g., due to exposure, travel, or medical conditions), to confirm vaccination success, or to monitor immunity after recovery from hepatitis B. It’s also used in screening for blood donors or before certain medical procedures.

What to Expect Before the Test

No special preparation is needed. A small needle will draw blood from a vein in your arm. You may feel a brief pinch, but it usually takes only a few minutes. If you’re nervous, let your provider know.

What the Results Mean

High levels of anti-HBs indicate strong immunity, whether from vaccination or prior infection. Low or absent levels suggest potential vulnerability to hepatitis B if exposed. Results are interpreted by your provider based on your medical history.

Possible Side Effects

Most people experience mild bruising, soreness, or swelling at the injection site. Rarely, there may be a slight fever or headache. If you develop severe pain, bleeding, or signs of infection (like redness or pus), contact your provider.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Anti-HBs IgG

Frequently asked questions

What does a positive result mean?
A positive result means your immune system has produced anti-HBs antibodies, indicating immunity—either from vaccination or past infection. This protects you from future hepatitis B virus exposure.
Can I get hepatitis B if my anti-HBs test is negative?
If your anti-HBs test is negative, you may not be immune to hepatitis B. If you’ve been exposed, your provider may recommend additional testing (like hepatitis B surface antigen) or vaccination to prevent infection.
How long does it take to get results?
Results are typically available within 1–3 business days, depending on your lab’s processing time. Your provider will discuss them with you during your follow-up visit.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy