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Fibrinogen (Plasma) Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of fibrinogen, a protein in your blood that plays a key role in blood clotting.

Quick summary

["Fibrinogen helps your blood clot properly and supports wound healing."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
21346-2
Short code
HTLV I+II Ab Patrn CSF IB-Imp
Synonyms
HTLV I+II Ab Patrn CSF IB-Imp
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ib
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

What Is Fibrinogen?

Fibrinogen is a blood protein produced by your liver. It’s essential for forming blood clots when you have an injury, helping to stop bleeding and prevent excessive loss of blood. Low levels may increase your risk of bleeding, while high levels could raise the risk of blood clots.

Why Might You Need This Test?

Doctors may order this test to check for bleeding disorders, monitor blood clotting problems, evaluate liver function, or assess conditions like DIC (disseminated intravascular coagulation), pregnancy complications, or certain cancers.

Sample Collection and Preparation

A blood sample is drawn from a vein, usually in your arm. The blood is then processed to separate plasma (the liquid part) for testing. This test is typically done on fresh plasma.

What Does the Result Mean?

Results are usually reported in grams per liter (g/L). While specific reference ranges can vary by lab, very low or very high levels may signal underlying health concerns that need further evaluation.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Low fibrinogen levels may indicate liver disease, severe infections, or conditions like DIC, where the body forms clots uncontrollably. High levels can be seen in pregnancy, inflammation, or certain cancers. Always discuss your results with your healthcare provider for personalized interpretation.

Short name

Fibrinogen

Frequently asked questions

How often should I get this test?
Fibrinogen testing is often done as part of a routine blood panel or when symptoms or conditions suggest bleeding or clotting issues. Your doctor will determine how often you need it based on your health needs.
What are common causes of abnormal fibrinogen levels?
Common causes of low fibrinogen include liver disease, severe infections, kidney problems, or certain medications. High fibrinogen levels may be linked to pregnancy, inflammation, infections, or cancer. Lifestyle factors like smoking or obesity can also influence blood protein levels.
Can diet or supplements affect fibrinogen levels?
Some foods rich in vitamin K (like leafy greens) or omega-3s (found in fish) may influence clotting factors, but fibrinogen itself is primarily produced by the liver. Always check with your doctor before making significant dietary changes, especially if you have a medical condition or are on medication.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy