Skip to content

Hemoglobin A1c (HbA1c) with 24-hour urine collection for total urinary creatinine

Published: August 9, 2026Updated: August 17, 2026

This test measures your average blood sugar levels over the past 2–3 months and checks your kidney function through urine creatinine. It helps track diabetes management and kidney health.

Quick summary

["Assesses long-term blood sugar control and kidney function in tandem."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
33665-1
Short code
HTLV I+II Ab Patrn Ser RIPA-Imp
Synonyms
HTLV I+II Ab Patrn Ser RIPA-Imp
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0
Ref high
17
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ripa
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What HbA1c Measures

HbA1c reflects the percentage of hemoglobin molecules attached to glucose over time, giving a snapshot of your blood sugar trends. It’s a key tool for diagnosing diabetes and monitoring treatment effectiveness.

Why Urine Creatinine Matters

Urine creatinine helps evaluate kidney function by measuring waste product excretion. Together with HbA1c, this profile provides a broader health picture, especially in patients with diabetes or suspected kidney issues.

How the Test Works

Your blood is tested for HbA1c levels, while a 24-hour urine sample is collected to measure creatinine. This combined approach ensures accurate tracking of both blood sugar and kidney health simultaneously.

When You Might Need This Test

This test is typically ordered for people with diabetes to monitor treatment progress, those with suspected kidney problems, or individuals at higher risk for metabolic or kidney-related conditions.

Reference range

NCBI: NSE 0-17 ng/mLN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HbA1c + Urine Creatinine Profile (24h)

Frequently asked questions

HbA1c alone can miss short-term blood sugar spikes, while creatinine alone doesn’t reflect glucose control. Combining these tests helps detect complications like diabetic nephropathy (kidney damage) earlier, guiding better management strategies.
Why is a 24-hour urine sample required for creatinine?
A 24-hour urine sample provides a more accurate measure of creatinine excretion, accounting for daily variations in kidney function and urine output. This helps assess kidney performance consistently over time.
What do abnormal HbA1c or creatinine results mean?
High HbA1c suggests poor blood sugar control, while elevated creatinine may indicate kidney strain. Both results should be discussed with your healthcare provider to adjust treatment plans, such as diet, medication, or monitoring frequency.
Your doctor will determine frequency based on your health status—typically annually for stable diabetes management, more often if complications arise or if kidney function is affected.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy