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Serum or plasma concentration of anti-HIV type 1 antibodies (qualitative immunoassay)

Published: August 9, 2026Updated: August 16, 2026

This test detects antibodies to the human immunodeficiency virus (HIV-1) in your blood or plasma. Antibodies are proteins your immune system makes in response to the virus.

Quick summary

["Determines if your body has developed immunity to HIV-1 after exposure."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
42769-0
Short code
HTLV I+II Ab Ser-Imp
Synonyms
HTLV I+II Ab Ser-Imp
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test checks for the presence of antibodies specific to HIV-1, which your immune system produces if it has encountered the virus. These antibodies are a sign that your body has been exposed to HIV-1, though they may not always indicate an active infection.

Why It’s Done

Healthcare providers may order this test to screen for HIV-1 infection, confirm a positive initial test result, or monitor individuals who have been exposed to the virus. It is also used in certain populations where HIV screening is recommended, such as sexually active adults or those with risk factors.

Sample Collection and Preparation

A blood sample is typically collected from a vein in your arm. The blood is then processed to separate serum or plasma, which is tested for HIV antibodies using an immunoassay method. This process helps ensure accurate detection of the antibodies without interference from other substances in the blood.

Test Method and Process

This test uses an immunoassay, which detects antibodies by measuring their interaction with HIV-1 antigens. The method may involve color changes or other indicators to confirm the presence of antibodies. Results are interpreted by a healthcare professional to determine if antibodies are present.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HIV Antibody Test (Qualitative)

Frequently asked questions

How long does it take to get results from this test?
Results are usually available within 24 to 72 hours, depending on the laboratory’s processing schedule. Your healthcare provider will contact you with the results once they are ready.
Can false results occur with this test?
While rare, false results can happen. False negatives may occur if the test is taken too early after exposure, and false positives can sometimes result from other infections or laboratory errors. Your healthcare provider will discuss the results in detail and may recommend additional testing if needed.
What does a positive result mean for my health?
A positive result means your body has antibodies to HIV-1, suggesting past or potential exposure. Further testing, such as HIV viral load or HIV RNA tests, may be needed to determine if you currently have an active infection. Early diagnosis and treatment are essential for managing HIV and improving health outcomes.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy