Skip to content

Total Bilirubin (Serum)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of bilirubin in your blood. Bilirubin is a yellow pigment produced when red blood cells break down, and it helps your liver process waste products.

Quick summary

["Bilirubin helps diagnose liver and bile duct issues, including jaundice and gallbladder problems."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
43296-3
Short code
HTLV I+II gp46 Ab Ser Ql
Synonyms
HTLV I+II gp46 Ab Ser Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to check for liver disease, bile duct blockages, or conditions like hemolytic anemia (where red blood cells break down too quickly). It can also help monitor treatments for these conditions.

What to Expect Before the Test

No special preparation is needed. You’ll provide a blood sample, usually drawn from your arm. If you’re on blood thinners, let your provider know before the test.

What the Results Mean

Higher than normal levels may indicate liver problems, bile duct issues, or red blood cell disorders. Lower levels are less common but could signal certain genetic conditions.

Common Conditions Monitored

This test is often used alongside others to diagnose jaundice (yellowing of skin/eyes), liver disease (like hepatitis), or blockages in the bile ducts.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Bilirubin Level

Frequently asked questions

What causes elevated bilirubin levels?
Elevated bilirubin can result from liver disease, bile duct blockages, or conditions that cause red blood cells to break down faster than the liver can process it.
How long does it take to get results?
Results are typically available within 1–3 business days, depending on your lab’s processing time.
Can diet affect bilirubin levels?
Dietary changes alone won’t alter bilirubin levels, but certain foods (like fatty foods) may affect bile flow indirectly. Follow your provider’s advice for any dietary restrictions related to your test.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy