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Serum or plasma concentration of total bilirubin

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of bilirubin in your blood, a yellow pigment produced when red blood cells break down. It helps assess liver function and detect conditions like jaundice or bile duct blockages.

Quick summary

["Your doctor may check bilirubin levels to diagnose or monitor liver or bile-related issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
77742-5
Short code
HTLV I+II Pnl SerPl IB
Synonyms
HTLV I+II Pnl SerPl IB
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ib
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Bilirubin is normally processed by your liver and excreted in bile. High levels can indicate problems like liver disease, gallbladder issues, or red blood cell disorders. Low levels may suggest certain genetic conditions or liver damage.

What to Expect Before the Test

No special preparation is needed, but you may be asked to fast for 8–12 hours before the test if your doctor specifies it. Bring your medical records or any medications you’re currently taking.

How the Test Works

A blood sample is drawn from a vein in your arm. The lab then measures the total bilirubin concentration in your serum or plasma using a standardized method, often automated and precise.

Common Conditions Monitored

Elevated bilirubin is often linked to jaundice (yellowing of skin/eyes), liver inflammation (hepatitis), bile duct obstructions, or hemolytic anemia. Doctors may also check it after liver surgery or trauma.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Total bilirubin

Frequently asked questions

Will I feel any pain or discomfort during the blood draw?
You may feel a slight pinch or sting when the needle is inserted, but it usually goes away quickly. Most people experience minimal discomfort afterward, though some may have a slight bruise or swelling at the site.
How long will it take to get my results?
Results are typically available within 1–3 business days, depending on your lab’s processing speed. Your doctor will discuss them with you during your follow-up visit.
Can I eat or drink before this test?
If fasting is required (check with your doctor), avoid food for 8–12 hours and liquids (except water) for the last 2 hours. If no fasting is needed, you can eat and drink normally.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy