Serum or plasma concentration of **total bilirubin**

Why Is This Test Done?

Your doctor may order a bilirubin test to check for liver diseases (like hepatitis or cirrhosis), blockages in the bile ducts, or conditions that cause red blood cells to break down too quickly (hemolytic anemia). It can also help evaluate jaundice (yellowing of skin/eyes) or monitor treatment for these conditions.

What to Expect Before the Test

No special preparation is needed. You’ll provide a blood sample (serum or plasma) or, less commonly, urine. If you’re tested for urine bilirubin, you may need to collect a 24-hour urine sample.

What the Results Mean

Higher-than-normal levels may indicate liver disease, bile duct issues, or red blood cell disorders. Lower-than-normal levels are rare but could suggest liver disease or certain genetic conditions. Your doctor will interpret results in the context of your symptoms and medical history.

Common Conditions Linked to Bilirubin Levels

Elevated bilirubin is often seen in conditions like hepatitis, gallstones, or bile duct blockages. Hemolytic anemia (rapid red blood cell destruction) can also raise levels. Low bilirubin is less common but may occur with liver disease or certain medications.