Skip to content

Antibody to Hepatitis B Core Antigen (IgG) - Serum/Plasma

Published: August 9, 2026Updated: August 16, 2026

This test detects antibodies against the hepatitis B core antigen, which can help identify past or current hepatitis B infection.

Quick summary

["This test helps track hepatitis B infection status over time."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
86550-1
Short code
HTLV I+II RNA Bld Ql NAA+probe
Synonyms
HTLV I+II RNA Bld Ql NAA+probe
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What Does This Test Measure?

The test measures IgG antibodies to hepatitis B core antigen (HBcAb IgG). These antibodies appear after the body has encountered the hepatitis B virus, indicating an immune response. They can persist long-term if the infection has resolved or if the person is chronically infected.

Why Might You Need This Test?

Your healthcare provider may order this test if you have risk factors for hepatitis B (e.g., exposure to infected blood, travel to high-risk regions, or certain occupations), if you’re vaccinated but have concerns, or as part of monitoring for chronic hepatitis B.

What Does a Positive Result Mean?

A positive result suggests you’ve had hepatitis B at some point. This could mean you recovered from an acute infection or are living with chronic hepatitis B. Further testing (like hepatitis B surface antibody or viral load) may be needed to clarify your status.

What Does a Negative Result Mean?

A negative result means you currently do not have detectable IgG antibodies to hepatitis B core antigen, but it doesn’t rule out past exposure. You may still need other tests to assess your hepatitis B risk or history.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Understanding Your Results

Short name

Hepatitis B Core Antibody (IgG)

Frequently asked questions

How often will I need follow-up tests?
Follow-up testing depends on your risk factors and results. If you’re vaccinated, a positive HBcAb IgG may prompt further evaluation (e.g., hepatitis B surface antibody, viral load) to determine if you’re immune or infected. If you’re chronically infected, your provider will guide ongoing monitoring.
Can I get hepatitis B from this test?
No, this test involves only blood samples and uses sterile, single-use equipment. The risk of infection from lab tests is extremely low.
What if I have a positive result but no symptoms?
A positive result doesn’t always mean symptoms are present. Chronic hepatitis B can be asymptomatic for years, so regular monitoring is important. Your provider will discuss next steps, such as blood tests or a liver evaluation, to assess your health.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy