Human T-lymphotropic virus type I/II antibody screening by serum
This test checks for antibodies to two related viruses that can cause chronic infections and certain health conditions, including a rare blood cancer (HTLV-associated myelopathy/tropical spastic paraparesis) and a skin disorder (Hodgkin-like lymphoma).
["Screening for antibodies to HTLV-I/II helps identify potential infection risk for serious long-term health effects."]
Key facts at a glance
- LOINC
- 14218-2
- Short code
- HTLV I p24 Ab Ser Ql
- Synonyms
- HTLV I p24 Ab Ser Ql
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Your healthcare provider may recommend this test if you have symptoms like unexplained fatigue, muscle weakness, nerve problems, or a history of exposure to the virus. It’s also sometimes ordered for blood donors or in certain high-risk groups (e.g., people from regions where HTLV is more common).
What to Expect Before the Test
No special preparation is needed. You’ll provide a blood sample, usually drawn from your arm. The process takes a few minutes, and you can resume normal activities afterward.
How the Test Works
The test detects antibodies in your serum using an immunoassay method. These antibodies are signs your immune system has recognized and fought the virus, but they don’t always mean you’re currently infected or at risk of severe illness.
What the Results Mean
A positive result means your blood contains antibodies to HTLV-I/II. This warrants further testing (like confirmation assays) to determine if you have active infection. A negative result suggests no detectable antibodies, but it doesn’t rule out past exposure.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
HTLV-I/II Antibody Screen
Frequently asked questions
What does a positive result mean?
Can I get this test at home?
How long does it take to get results?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy