Hemoglobin A1c (HbA1c) with 24-Hour Urine Collection for Creatinine Adjustment
This test measures your average blood sugar levels over the past 2–3 months, adjusted for kidney function using a 24-hour urine sample. It helps assess long-term diabetes control and kidney health.
["This test combines HbA1c with urine creatinine to refine diabetes management by accounting for kidney function."]
Key facts at a glance
- LOINC
- 93191-5
- Short code
- HTR2C c.-759C>T Geno Bld/T
- Synonyms
- HTR2C c.-759C>T Geno Bld/T
- Category
- chemistry
- Sample
- whole-blood
- Container
- Lavender-top (EDTA)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- molgen
- Specimen volume
- 3 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Your doctor may order this test if you have diabetes and need a more precise way to track blood sugar trends, especially if kidney function varies. It also helps adjust for differences in kidney processing that might affect standard HbA1c results.
How the Test Works
Blood is drawn to measure HbA1c, while a 24-hour urine sample is collected to assess creatinine levels. The creatinine data helps correct the HbA1c result for kidney function, providing a more accurate reflection of your average blood sugar.
What to Expect Before the Test
No special preparation is needed for the blood draw, but you’ll need to collect a full 24-hour urine sample starting after your first morning void. Follow your healthcare provider’s instructions for timing and storage.
What the Results Mean
The final result combines your HbA1c percentage with creatinine data to give a refined estimate of your long-term blood sugar control. Lower creatinine levels may slightly lower the adjusted HbA1c, while higher levels may slightly raise it.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
HbA1c (Creatinine-Adjusted Urine)
Frequently asked questions
This test is particularly useful for patients with kidney disease or fluctuating kidney function, as it provides a more accurate picture of diabetes management without relying solely on kidney function alone. It helps tailor treatment plans to better reflect your actual blood sugar control.
An abnormal result may indicate poor long-term blood sugar control (if HbA1c is high) or potential kidney issues (if creatinine is elevated). Your doctor will discuss these findings in the context of your overall health.
Your doctor will determine how often you need this test based on your diabetes management plan and kidney health. Regular monitoring helps track progress and adjust treatments as needed.
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy