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Hemoglobin A1c (HbA1c) with 24-hour urine collection for creatinine clearance

Published: August 9, 2026Updated: August 16, 2026

This test measures your average blood sugar levels over the past 2–3 months and checks how well your kidneys are functioning.

Quick summary

["Helps track diabetes management and kidney health in tandem."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
101231-9
Short code
Hu Ab CSF Ql IB
Synonyms
Hu Ab CSF Ql IB
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ib
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

What HbA1c Measures

HbA1c reflects the percentage of hemoglobin in your red blood cells that is coated with sugar (glycated). It’s a key indicator of long-term blood sugar control, useful for diagnosing diabetes and assessing treatment effectiveness. A higher HbA1c suggests poorer control over time.

How Kidney Function Is Evaluated

The urine test measures creatinine clearance, a measure of how well your kidneys filter waste from blood. This helps assess kidney function and identify early signs of kidney damage.

Why This Test Combines Both Measures

Combining HbA1c with creatinine clearance provides a more comprehensive picture of your health. High blood sugar can damage kidneys over time, and kidney issues may affect how well your body processes medications or nutrients.

When This Test Is Ordered

Your doctor may order this test if you have diabetes, high blood sugar, or symptoms of kidney problems (e.g., fatigue, swelling, frequent urination). It’s also used during routine check-ups for patients at risk of diabetes or kidney disease.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HbA1c + Kidney Function Test

Frequently asked questions

What does an abnormal HbA1c result mean?
An elevated HbA1c suggests your blood sugar has been consistently higher than recommended. This may mean your diabetes treatment needs adjustment, or you may need lifestyle changes (like diet, exercise, or medication) to improve control.
How does creatinine clearance relate to kidney health?
Creatinine clearance helps assess how well your kidneys filter waste. Low levels may indicate reduced kidney function, which can be linked to diabetes, high blood pressure, or other health issues. Your doctor may recommend further testing or adjustments to your care plan if results are concerning.
Can I fast before this test?
No fasting is required for HbA1c, but you may need to collect a 24-hour urine sample without dietary restrictions (except for certain medications or supplements). Follow your lab’s specific instructions for timing and preparation.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy