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Human Immunodeficiency Virus (HIV) Antibody Screening, Serum/Plasma

Published: August 9, 2026Updated: August 16, 2026

This test detects antibodies to the human immunodeficiency virus (HIV), which your body produces in response to infection. It helps determine if you’ve been exposed to HIV.

Quick summary

["This screening helps identify potential HIV exposure early for further evaluation and care."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
31536-6
Short code
Hu IgG Ser-aCnc
Synonyms
Hu IgG Ser-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test looks for antibodies against HIV, a virus that attacks the immune system. These antibodies develop after exposure and can remain in your blood for years. The presence of these antibodies suggests past or current infection, though they may not always confirm active HIV infection alone.

Why It’s Done

Doctors may order this test if you have risk factors for HIV (e.g., unprotected sex, shared needles, or exposure to infected blood), symptoms of HIV-related illness, or if you’re part of a group at higher risk. It’s also used as part of routine screening in certain settings.

What to Expect Before the Test

No special preparation is needed. You’ll provide a blood sample, usually from a vein in your arm. The process is quick and typically painless, though you may feel a slight pinch. If you’re nervous, let your healthcare provider know.

What to Expect After the Test

Most people experience minimal discomfort after the blood draw. Apply gentle pressure to the site to stop any bleeding. Avoid vigorous activity for a few hours. If you have questions about results, discuss them with your provider.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Positive results indicate the presence of HIV antibodies, which may mean past or current infection. However, false positives can occur, so further testing (like a confirmatory HIV antibody test or viral load test) is needed to confirm diagnosis. Early detection allows for timely treatment and management to improve health outcomes.

Short name

HIV Antibody Screen

Frequently asked questions

How soon can I get my results?
Results are typically available within 1 to 3 business days, depending on lab processing times. Your healthcare provider will discuss the results with you and guide next steps, if needed.
What does a positive result mean?
A positive test means your blood contains HIV antibodies, suggesting possible exposure. This does not confirm HIV infection alone—additional tests are required to diagnose HIV. Treatment options and support will depend on your results and healthcare team’s recommendations.
Can I still have sex or share needles if my test is positive?
No. If your test is positive, you should avoid high-risk behaviors (like unprotected sex or needle sharing) and follow your healthcare provider’s guidance for safe practices, treatment, and support. HIV can be managed with medication, and early care improves long-term health outcomes.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy