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Hemoglobin A1c (HbA1c) with 24-hour urine collection for measurement of urinary excretion

Published: August 9, 2026Updated: August 16, 2026

This test measures how much of your hemoglobin A1c appears in your urine over a 24-hour period, which can help assess how consistently your blood sugar is controlled.

Quick summary

["Understanding how much HbA1c is excreted in urine helps track long-term blood sugar management beyond just the standard HbA1c test."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
111403-2
Short code
HVA Msmt Ur
Synonyms
HVA Msmt Ur
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if they suspect you have unusual patterns of blood sugar control, such as frequent spikes or drops, or if you have conditions like kidney disease that affect how hemoglobin is processed. It can also help monitor how well medications are working over time.

What to Expect Before the Test

You’ll need to collect all urine for a full 24-hour period, typically starting after you urinate in the morning of the first day. Store the urine in a refrigerator and bring the entire sample to the lab. Follow any specific instructions your provider gives you to ensure accurate results.

What Happens During the Test

The lab analyzes the collected urine sample to measure the amount of hemoglobin A1c that has been excreted. This involves specialized testing to detect and quantify the substance in your urine.

What the Results Mean

While standard HbA1c tests measure average blood sugar over three months, this urine test provides insight into how much of your hemoglobin is being broken down and excreted daily. Higher levels may indicate conditions like kidney disease or other metabolic issues affecting hemoglobin metabolism.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HbA1c Urine Excretion Profile

Frequently asked questions

What does a high urinary HbA1c excretion mean?
A high urinary excretion of HbA1c may suggest your kidneys are not filtering hemoglobin efficiently, which could be linked to kidney disease, diabetes complications, or other metabolic disorders. It’s important to discuss these results with your healthcare provider to explore further causes and next steps.
How often should I get this test?
The frequency depends on your health status and treatment plan. Your provider may recommend this test periodically if you have diabetes, kidney issues, or other conditions affecting hemoglobin metabolism. Follow their guidance for the best timing and intervals.
Can diet or medications affect this test?
Yes, certain medications (like some diuretics or blood pressure drugs) and dietary factors (such as protein intake) can influence hemoglobin metabolism and urinary excretion. Always inform your healthcare provider about all medications and supplements you’re taking to ensure accurate results and interpretation.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy