Hydromorphone concentration in plasma (24-hour urine collection)
This test measures the amount of hydromorphone, a pain medication, in your urine over a 24-hour period. It helps track drug use, adherence to treatment, or exposure after administration.
["This test assesses long-term hydromorphone levels in your urine."]
Key facts at a glance
- LOINC
- 73341-0
- Short code
- HYDROmorphone ind plt IgG SerPl Ql FC
- Synonyms
- HYDROmorphone ind plt IgG SerPl Ql FC
- Category
- hematology
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- flow-cytometry
- CPT
- 82784
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Your healthcare provider may order this test to monitor your use of hydromorphone, especially if you’re prescribed it for pain management. It can also help confirm whether you’ve taken the medication as directed or if there’s evidence of misuse. In some cases, it may be used in drug testing or to evaluate compliance with treatment plans.
What to Expect Before the Test
You’ll need to collect all urine produced in a 24-hour period, typically starting after midnight and ending the next midnight. Collect samples in a series of containers, keeping the first and last voids separate if instructed. Follow your provider’s specific instructions to ensure accurate results.
What Happens During the Test
No special preparation is needed beyond collecting your urine sample. The sample is sent to a lab for analysis, where it is tested for hydromorphone levels using a sensitive detection method.
What the Results Mean
Results are reported as the concentration of hydromorphone in your urine. Higher levels may indicate recent use, improper dosing, or potential misuse. Your healthcare provider will interpret the results in the context of your medical history and treatment goals.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
Urine Hydromorphone (24h)
Frequently asked questions
What does a high level of hydromorphone in urine mean?
What does a low or undetectable level mean?
Can this test detect hydromorphone from other sources?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy