Hydromorphone concentration in plasma (quantitative)
This test measures the amount of hydromorphone, a pain medication, in your blood plasma. It helps doctors monitor your drug levels, especially if you’re taking it for chronic pain or managing opioid-related conditions.
["This test helps ensure your pain medication stays at a safe and effective level."]
Key facts at a glance
- LOINC
- 73340-2
- Short code
- HYDROmorphone ind plt IgM SerPl Ql FC
- Synonyms
- HYDROmorphone ind plt IgM SerPl Ql FC
- Category
- hematology
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- flow-cytometry
- CPT
- 82784
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Your doctor may order this test if you’re taking hydromorphone regularly—such as for severe pain, cancer treatment, or opioid use disorder—to check if your dose is working properly. It’s also used in cases of suspected overdose or to adjust medication based on how your body processes it.
What to Expect Before the Test
No special preparation is needed. You’ll likely have a small needle inserted into your arm or vein to draw a blood sample. The process is quick and usually painless. If you’re on blood thinners, let your doctor know before the test.
What the Results Mean
Results show how much hydromorphone is in your blood at the time of testing. High levels may indicate overdose risk, while low levels could mean your medication isn’t working as intended. Your doctor will interpret these results in the context of your medical history and symptoms.
Common Reasons for Testing
Doctors test for hydromorphone to confirm proper dosing, detect drug interactions, or assess compliance with treatment plans. It’s also used in cases of suspected opioid poisoning or to monitor long-term opioid therapy.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance: Hydromorphone Levels and Health
Short name
Hydromorphone Level
Frequently asked questions
What causes elevated hydromorphone levels?
How do hydromorphone levels change over time?
Can diet or lifestyle affect hydromorphone test results?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy