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Hydroxyzine concentration in plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of hydroxyzine, a medication used to treat anxiety, allergies, or itching, in your blood plasma. It helps assess drug levels for therapeutic monitoring.

Quick summary

["This test checks if your hydroxyzine dose is within safe and effective ranges."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
73338-6
Short code
hydrOXYzine ind plt IgM SerPl Ql FC
Synonyms
hydrOXYzine ind plt IgM SerPl Ql FC
Category
hematology
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
flow-cytometry
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you’re taking hydroxyzine long-term, have unusual side effects, or if you’re experiencing symptoms that might be related to drug levels. It can also be used to confirm compliance with your medication regimen.

What to Expect Before the Test

No special preparation is needed. You may have a small needle inserted into your arm to draw blood. The process usually takes a few minutes, and you’ll feel minor discomfort for a short time.

What the Test Results Mean

Results are compared to general reference ranges for hydroxyzine in plasma. Low levels may indicate insufficient medication, while very high levels could signal overdose or improper metabolism.

Common Side Effects to Watch For

Hydroxyzine can cause drowsiness, dry mouth, or dizziness. If you experience severe symptoms like confusion, slow breathing, or extreme fatigue, contact your doctor immediately.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Hydroxyzine levels help prevent toxicity or inadequate treatment. For example, high levels may require dose adjustments, while low levels could prompt a prescription review. This test is particularly useful in patients with liver or kidney issues, as these organs play a key role in metabolizing the drug.

Short name

Hydroxyzine Level

Frequently asked questions

Why might my doctor request this test?
Your doctor may order this test to ensure your hydroxyzine dose is working as intended, especially if you’re experiencing symptoms like drowsiness, confusion, or persistent itching that don’t improve with the medication.
What does a low or high hydroxyzine level mean?
A low level might mean your body isn’t absorbing enough medication, while a high level could indicate improper metabolism or overdose. Your doctor will discuss results with you and adjust your treatment plan if needed.
Can I eat or drink before this test?
You can eat and drink normally before the test, as no special preparation is required. However, inform your healthcare provider if you’re taking other medications that might affect blood tests.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy