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Hypoxanthine in Cerebrospinal Fluid (CSF) – Substance Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of hypoxanthine, a chemical related to energy production, in your spinal fluid. It may be used to assess certain neurological conditions.

Quick summary

["This test helps evaluate metabolic or neurological issues in spinal fluid."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
75123-0
Short code
Hypoxanthine CSF-sCnc
Synonyms
Hypoxanthine CSF-sCnc
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

Why Might This Test Be Ordered?

Your healthcare provider may recommend this test if you have symptoms like headaches, neurological problems, or suspected metabolic disorders. It could also be part of a broader evaluation for conditions affecting the brain or spinal cord.

What Does the Sample Need to Be Collected?

A small amount of cerebrospinal fluid is collected through a procedure called a lumbar puncture (spinal tap). This involves inserting a needle into your lower back to draw fluid from your spinal canal.

How Is the Test Performed?

The collected CSF sample is analyzed using a specialized laboratory technique to measure hypoxanthine concentration. The method may involve high-performance liquid chromatography (HPLC) or another precise analytical approach.

What Are Common Causes for Testing?

While hypoxanthine in CSF is not commonly measured for routine screening, elevated levels may be associated with rare metabolic disorders, mitochondrial diseases, or certain neurological conditions. Your doctor will consider your symptoms and medical history.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Hypoxanthine CSF

Frequently asked questions

What does a normal result mean?
A normal result does not rule out all possible conditions, as hypoxanthine levels can vary based on metabolic state and underlying health. Your doctor will discuss findings in the context of your symptoms and medical history.
How soon will I get results?
Results are typically available within 1–3 business days, depending on laboratory processing times. Your healthcare provider will contact you with the outcome and next steps.
Is this test painful?
The lumbar puncture procedure may cause mild discomfort, but it is generally well-tolerated. You may experience a brief ache or stiffness afterward. Follow your doctor’s instructions for recovery.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy