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Immunoassay for IgE Antibody to Cigarette Smoke Extract (Serum)

Published: August 9, 2026Updated: August 16, 2026

This test measures your immune system’s response to cigarette smoke by detecting specific antibodies (IgE) in your blood. It may help identify sensitivities or allergic reactions to smoke exposure.

Quick summary

["Assesses potential allergic or immune response to cigarette smoke exposure."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
33960-6
Short code
IC IgE SerPl-aCnc
Synonyms
IC IgE SerPl-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

IgE antibodies are part of your immune system’s defense mechanism. When your body encounters allergens like cigarette smoke, it may produce IgE antibodies as part of an allergic reaction. This test specifically looks for IgE directed toward proteins found in cigarette smoke.

Why It Might Be Ordered

Your healthcare provider may recommend this test if you suspect an allergic reaction to cigarette smoke, have symptoms like sneezing, coughing, or skin irritation after exposure, or if you’re evaluating environmental or occupational sensitivities.

How the Test Works

A small blood sample is taken from your arm. The sample is then analyzed using an immunoassay method to detect IgE antibodies that bind to cigarette smoke proteins. This process identifies if your immune system has recognized these components as foreign.

What to Expect Before the Test

No special preparation is needed. You may eat and drink normally before the test, but inform your provider about any medications you’re taking, as some can affect blood tests.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Cigarette Smoke IgE

Frequently asked questions

Can this test detect long-term health effects from smoking?
No, this test specifically measures an immediate immune response (IgE antibodies) to cigarette smoke. It does not assess long-term health risks like lung disease or cancer, which would require additional tests.
What if my test result is positive?
A positive result indicates your immune system may react to cigarette smoke. Discuss your findings with your provider to explore symptoms, exposure history, and next steps for managing your health, such as reducing exposure or allergy treatments.
Does this test replace a smoking cessation program?
No, this test is a diagnostic tool to evaluate immune responses. It does not replace medical advice or programs focused on quitting smoking, which are essential for overall health benefits.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy