Skip to content

Immunoassay for IgG Subclass 1 (IgG1) Antibody Concentration in Serum

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of a specific type of antibody (IgG1) in your blood serum. Antibodies are proteins that help your immune system fight infections.

Quick summary

["IgG1 antibodies are part of your immune response and can be important for long-term protection against diseases."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
42639-5
Short code
IC IgG SerPl C1Q Bind-aCnc
Synonyms
IC IgG SerPl C1Q Bind-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
c-q-binding-assay
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

IgG1 antibodies are one of four subclasses of Immunoglobulin G (IgG), the most common antibody in your blood. This test specifically looks at the concentration of IgG1 antibodies, which play a key role in defending against bacteria and viruses. They are also involved in allergic reactions and some autoimmune conditions.

Why Might You Need This Test?

Your healthcare provider may order this test if you have symptoms or conditions related to immune system function, such as recurrent infections, autoimmune diseases, or allergies. It could also be part of monitoring treatment for conditions affecting antibody levels.

How Is the Test Performed?

A blood sample is taken from a vein in your arm. The blood is then processed to separate the serum, which is sent to a lab for testing using an immunoassay method. This method detects and measures the presence and concentration of IgG1 antibodies in your serum.

What Are Possible Results?

Results are typically reported as a concentration value (in mg/mL or similar units) compared to a reference range. However, reference ranges can vary by lab and individual factors, so your results will be interpreted by your healthcare provider.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

IgG1 Antibody Level

Frequently asked questions

What Does an Abnormal Result Mean?
An abnormal result may suggest an underlying health condition that requires further evaluation. Your doctor will discuss the results with you and may recommend additional tests or treatments based on your specific situation.
How Often Should I Get This Test?
The frequency of this test depends on your medical condition and treatment plan. Your healthcare provider will let you know how often you need to be tested, usually based on your symptoms or monitoring needs.
Can I Make Any Changes Before the Test?
Try to avoid taking any medications that might affect antibody levels unless instructed by your doctor. Also, inform your healthcare provider about any recent illnesses or vaccinations, as these can temporarily influence antibody concentrations.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy