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Serum or Plasma Substance Concentration by Immunoassay (General Protein or Antibody Screening)

Published: August 9, 2026Updated: August 16, 2026

This test measures certain proteins or antibodies in your blood, often used to check for infections, immune responses, or other health conditions.

Quick summary

["Helps identify potential immune system issues or infections by detecting specific proteins/antibodies in your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
17020-9
Short code
ICS Ab Ser Ql IF
Synonyms
ICS Ab Ser Ql IF
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
if
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

This test uses an immunoassay method to detect and quantify specific proteins or antibodies in your serum or plasma. Immunoassays are highly sensitive and can identify a wide range of substances, including markers for infections, autoimmune diseases, or other conditions. The test may screen for a broad category of analytes rather than a single specific protein.

Why Your Doctor Might Order This Test

Your doctor may recommend this test to evaluate your immune system, diagnose infections (such as viral or bacterial), check for autoimmune conditions, or monitor certain treatments. It can also be part of routine screening or follow-up care depending on your medical history.

Common Uses and Conditions

Common uses include detecting antibodies against infections (e.g., viruses like HIV, hepatitis, or COVID-19), screening for autoimmune diseases (e.g., rheumatoid arthritis, lupus), or identifying proteins linked to inflammation or other systemic conditions.

Sample Collection and Preparation

Blood is drawn from a vein, typically in your arm. The blood sample is then processed to separate serum (liquid part after clotting) or plasma (liquid part before clotting). This sample is sent to a lab for testing using an immunoassay method.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

The presence or level of certain proteins or antibodies can indicate underlying health issues. For example, elevated antibody levels may signal an active infection or an overactive immune response. Low or abnormal levels might suggest immune deficiencies or other conditions requiring further medical evaluation. Always discuss results with your healthcare provider.

Short name

Protein/antibody screening

Frequently asked questions

How long does it take to get results?
Results from this test are usually available within 1 to 3 business days, depending on the lab and your healthcare provider’s workflow. Your doctor will contact you once the results are ready.
What does a positive or abnormal result mean?
A positive or abnormal result means your blood contains higher or lower-than-expected levels of the measured proteins or antibodies. This could indicate an infection, autoimmune condition, or other health concern. Your doctor will interpret the results in the context of your medical history and symptoms to guide further testing or treatment.
Can I eat or drink before this test?
For most blood tests, including this one, you can eat and drink normally unless your doctor specifies otherwise. However, avoid alcohol for 24 hours before the test if instructed by your healthcare provider.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy