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Intermediate Density Lipoprotein Cholesterol, Serum/Plasma — Substance Concentration

Published: August 9, 2026Updated: August 16, 2026

Measures intermediate density lipoprotein (IDL) cholesterol in blood. It is sometimes used to help assess cholesterol metabolism and cardiovascular risk.

Quick summary

["IDL cholesterol is a blood measurement used with other lipid results to help assess cardiovascular risk."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
70201-9
Short code
IDLc SerPl-sCnc
Synonyms
IDLc SerPl-sCnc
Category
lipid
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This test measures the amount of cholesterol carried in intermediate density lipoproteins (IDL) in serum or plasma. IDL is a cholesterol-containing particle that circulates between other types of lipoproteins.

Why might I need this test?

IDL cholesterol may be measured as part of an assessment of lipid metabolism or cardiovascular risk. It is usually interpreted together with total cholesterol, LDL cholesterol, HDL cholesterol, triglycerides, and your medical history.

How is the test performed?

A blood sample is collected, and the laboratory separates serum or plasma and measures IDL cholesterol using a validated laboratory method. The result is reported as a concentration in the blood.

How do I prepare for the test?

Follow your clinician's instructions about fasting. If fasting is requested, avoid food and beverages other than water for the specified period. Tell the laboratory if you are taking cholesterol-lowering medicines, because treatment can affect the result.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

IDL cholesterol

Frequently asked questions

Is IDL cholesterol the same as LDL cholesterol?
No. IDL and LDL are different types of cholesterol-carrying particles, although they are related and both may contribute to cardiovascular risk.
Do I need to fast for this test?
Fasting may be requested, especially when IDL is being assessed with other lipid measurements. Follow the specific instructions provided by your clinician or laboratory.
Can medications affect IDL cholesterol?
Yes. Cholesterol-lowering treatments and certain other medicines may change blood lipid levels. Tell your healthcare professional about medications and supplements when the test is ordered.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy