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IDL-C and VLDL-3 Cholesterol, Serum/Plasma — Substance Concentration

Published: August 9, 2026Updated: August 16, 2026

A specialized cholesterol test measuring intermediate-density and VLDL-3 lipoprotein cholesterol to help assess atherogenic remnant lipoproteins.

Quick summary

["This test measures cholesterol carried by certain remnant lipoproteins that may contribute to cardiovascular risk."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
70202-7
Short code
IDLc+VLDL3c SerPl-sCnc
Synonyms
IDLc+VLDL3c SerPl-sCnc
Category
lipid
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0
Ref high
100
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
83721
SNOMED
113079007
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This blood test measures cholesterol in intermediate-density lipoproteins (IDL-C) and very-low-density lipoprotein subtype 3 particles (VLDL-3C). These lipoproteins transport cholesterol and triglycerides through the bloodstream.

Why might I need this test?

It may be ordered to evaluate cholesterol carried by remnant lipoproteins, particularly in someone with high triglycerides, abnormal cholesterol results, or cardiovascular risk factors. It is usually interpreted alongside a complete lipid panel.

How is the test performed?

A blood sample is drawn and separated into serum or plasma. A laboratory then measures the cholesterol content of the specified lipoprotein fractions using specialized laboratory methods.

How do I prepare for the test?

Fasting for 8 to 12 hours may be required, and water is generally allowed. Follow the instructions provided with the order; do not stop prescribed medication unless your clinician tells you to do so.

Reference range

Optimal: <100 mg/dLN/A

Specimen: serum

Fasting for 12-14 hours preferred. Water is permitted. Avoid alcohol for 24 hours before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

IDL-C and VLDL-3 cholesterol

Frequently asked questions

What are IDL-C and VLDL-3 cholesterol?
IDL-C is cholesterol carried by intermediate-density lipoproteins, while VLDL-3C is cholesterol carried by a very-low-density lipoprotein subtype. These particles are part of the triglyceride-rich remnant pathway.
Does a high result mean I have heart disease?
No. A high result can indicate increased atherogenic cholesterol particles, but it does not diagnose heart disease. Your clinician will interpret it with your other lipid results, medical history, and risk factors.
Is this test the same as a standard LDL cholesterol test?
No. Standard LDL cholesterol measures a broader LDL fraction, while this test focuses on IDL and VLDL-3 remnant lipoprotein cholesterol. It is usually used as a specialized addition to a standard lipid panel.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy