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Immunoglobulin A (IgA) in Serum (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of Immunoglobulin A, a type of antibody in your blood serum, which helps protect against infections.

Quick summary

["IgA helps fight bacteria and viruses, and low levels may indicate immune system issues or certain health conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
6886-6
Short code
IgA1 Ser-mCnc
Synonyms
IgA1 Ser-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

IgA is one of the key proteins in your immune system. It helps defend against harmful bacteria and viruses that enter your body through mucous membranes, like those in your nose, throat, and digestive tract. This test helps doctors assess your immune response and identify potential problems with how your body produces antibodies.

Why Might You Need This Test?

Your doctor may order this test if you have symptoms like frequent infections, digestive issues, or if they suspect an immune disorder. It can also be part of a broader evaluation for conditions like celiac disease, lupus, or other autoimmune diseases.

What to Expect Before the Test

No special preparation is needed for this blood test. You may have a small needle inserted into your arm to draw a blood sample. The process usually takes a few minutes, and you can resume normal activities afterward.

What Are Possible Results?

Results are typically reported as a mass concentration of IgA in the blood. While reference ranges can vary by lab, they generally fall within a specific range for healthy individuals. Your doctor will interpret the results in the context of your overall health and symptoms.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

IgA Serum Level

Frequently asked questions

What causes low IgA levels?
Low IgA levels can be caused by genetic factors, certain autoimmune diseases, chronic infections, or immune system disorders. It may also occur in people with conditions like celiac disease or after certain treatments like chemotherapy.
What are the symptoms of low IgA levels?
Symptoms may include frequent infections (especially in the sinuses, lungs, or digestive tract), chronic diarrhea, or recurrent mouth ulcers. Some people with low IgA may not have noticeable symptoms at all.
Can IgA levels change over time?
Yes, IgA levels can fluctuate due to illness, immune responses, or certain medications. Repeating the test after a few months may help track changes, especially if you have ongoing symptoms or a suspected immune issue.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy