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Immunoglobulin G (IgG) 24-Hour Urinary Excretion

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of Immunoglobulin G, a type of antibody, found in your urine over a 24-hour period. It helps assess kidney function and the body’s immune response.

Quick summary

["This test helps evaluate kidney health and immune system activity through urine IgG levels over a full day."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
44388-7
Short code
IgA 24h Ur Ql IFE
Synonyms
IgA 24h Ur Ql IFE
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
immunofixation
CPT
82784
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if they suspect kidney problems, such as glomerular diseases (e.g., IgA nephropathy), or to monitor immune-related conditions. It can also help diagnose or track conditions affecting antibody excretion, like certain autoimmune diseases or urinary tract issues.

What to Expect Before the Test

No special preparation is usually needed. You’ll collect all your urine for a full 24 hours, starting and ending the collection period at the same time each day. Store the urine in a cool place or refrigerator until you deliver it to the lab.

What Happens During the Test

The lab analyzes the collected urine sample to measure IgG levels. The test may be performed using immunoassay methods to detect and quantify the antibody.

What the Results Mean

Results are compared to expected ranges for healthy individuals. Elevated levels may indicate kidney disease, immune disorders, or other conditions affecting antibody excretion. Lower levels could suggest kidney dysfunction or other health issues.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

IgG Urine

Frequently asked questions

How is IgG measured in urine?
IgG in urine is measured using immunoassay techniques, which detect and quantify the antibody. These methods are sensitive and accurate for identifying IgG presence and concentration.
Elevated IgG in urine can be due to kidney diseases (like IgA nephropathy), immune disorders, or conditions causing abnormal antibody excretion. Chronic kidney disease or certain infections may also play a role.
Dietary factors may indirectly influence kidney function, which could affect IgG excretion, but they do not directly alter IgG levels in urine. Stick to your provider’s advice regarding fluid intake and dietary restrictions if recommended.
When should I follow up with my doctor?
Follow up if you have persistent symptoms like swelling, frequent urination, or unexplained fatigue. Your doctor will interpret results in the context of your overall health and may recommend further testing or adjustments to treatment.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy