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Immunoglobulin G (IgG) Subclass 1 (Serum) Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of Immunoglobulin G subclass 1 (IgG1), a type of antibody in your blood. IgG1 helps protect your body from infections and plays a role in immune responses.

Quick summary

["IgG1 helps fight infections and supports immune function; levels may indicate immune health or response to treatments."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
10489-3
Short code
IgA HC Ag Tiss Ql ImStn
Synonyms
IgA HC Ag Tiss Ql ImStn
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
immune-stain
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may order this test to evaluate your immune system, check for immune deficiencies, monitor treatment responses (like for autoimmune diseases or infections), or assess antibody production in conditions such as HIV, hepatitis, or certain cancers. It may also be used in research or specialized diagnostic scenarios.

What to Expect Before the Test

No special preparation is needed. You may have a small needle inserted into your arm to draw blood. If you’re on blood thinners or have a history of bleeding issues, let your provider know. Avoid alcohol for 24 hours before testing if instructed.

What the Results Mean

Results are compared to a general reference range for healthy adults. Low levels might suggest immune problems, while high levels could indicate overactive immune responses or certain medical conditions. Your provider will interpret results in the context of your overall health.

Common Conditions Affecting IgG1 Levels

IgG1 levels can be lower in people with immune disorders (e.g., HIV/AIDS, certain autoimmune diseases), chronic infections, or conditions affecting antibody production. High levels may be seen in chronic infections, some cancers, or inflammatory diseases. Always discuss results with your doctor.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

IgG1 Level

Frequently asked questions

How long does it take to get my IgG1 test results?
Results are typically available within 1–3 business days, depending on your lab’s processing time. Your healthcare provider will contact you once they’re ready, or you may receive a digital copy of the report if applicable.
Can I eat or drink before this test?
You can eat and drink normally unless instructed otherwise. No fasting is required for this blood test.
Is there anything I should avoid before the blood draw?
Avoid excessive alcohol for 24 hours before testing if your provider recommends it. Otherwise, follow any specific instructions they give you, such as stopping certain medications temporarily.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy