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Immunoglobulin G (IgG) Subclass 2 Concentration (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of Immunoglobulin G (IgG) subclass 2 antibodies in your blood. IgG is part of your immune system and helps fight infections.

Quick summary

["IgG2 levels help doctors understand how well your immune system is producing this specific type of antibody."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
13312-4
Short code
IgA IgG SerPl-aCnc
Synonyms
IgA IgG SerPl-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may order this test if you have symptoms of a weakened immune system, recurrent infections, or conditions like asthma, allergies, or certain autoimmune diseases. It may also be used to monitor treatment responses in conditions affecting antibody production.

What to Expect Before the Test

No special preparation is needed. You may have a small needle inserted into a vein in your arm, and a blood sample will be drawn. This is usually done in a clinic or lab setting.

What the Test Results Mean

Results may be compared to a reference range to see if your IgG2 levels are within normal limits or if they are lower or higher than expected. Lower levels might suggest immune system issues, while higher levels could indicate other health conditions or immune responses.

IgG2 deficiency can make it harder for your body to fight certain types of infections, especially those caused by bacteria like *Streptococcus* or *Pneumococcus*. Conditions like asthma or allergies might also be associated with variations in IgG2 levels.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

IgG2 plays a role in protecting against certain bacterial infections and allergic responses. Low IgG2 levels can indicate a specific immune deficiency that may require further evaluation or treatment, such as immune-boosting therapies. High levels may be seen in chronic infections, autoimmune diseases, or other immune system activations.

Short name

IgG2 Level

Frequently asked questions

What does a low IgG2 level mean?
A low IgG2 level might suggest an immune system issue that could affect your ability to fight certain infections. This could be part of a broader immune deficiency or a specific IgG subclass deficiency. Your doctor will discuss further steps, such as additional tests or treatments, if needed.
How is IgG2 tested?
IgG2 levels are measured using an immunoassay method, which detects the specific antibodies in your blood. A small blood sample is taken, usually from a vein in your arm, and sent to a lab for analysis.
Can IgG2 levels change over time?
Yes, IgG2 levels can fluctuate due to infections, immune responses, aging, or certain medications. Regular monitoring may be recommended if you have a known immune condition or if your levels are consistently outside the normal range.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy