Skip to content

Immunoglobulin E (IgE) mass concentration in serum/plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of Immunoglobulin E (IgE), a type of antibody in your blood. IgE is linked to allergic reactions and certain immune responses.

Quick summary

["IgE levels help diagnose allergies or immune disorders."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
48665-4
Short code
IgA.IT Ser+CSF-mCnc
Synonyms
IgA.IT Ser+CSF-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order this test to check for allergies, asthma, or conditions like chronic urticaria (hives), eczema, or parasitic infections. It can also help evaluate immune system function or monitor treatment responses.

What to Expect Before the Test

No special preparation is needed. You may have a small needle inserted into your arm or vein to draw blood. If you’re nervous, let your healthcare provider know—they can help make it more comfortable.

What the Results Mean

Results are interpreted based on your symptoms and medical history. High IgE levels often suggest allergies or immune-related conditions, while very low levels may indicate immune deficiencies or certain infections.

Common Conditions Linked to IgE Levels

Elevated IgE is commonly found in allergic disorders (e.g., hay fever, food allergies), asthma, or parasitic infections. Very low IgE might be seen in rare immune disorders or after certain treatments.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

IgE Level

Frequently asked questions

What causes IgE levels to change?
IgE levels can rise due to allergens (like pollen or pet dander), infections (e.g., parasites), or autoimmune conditions. They may also drop after certain treatments (e.g., immunotherapy) or in rare immune deficiencies.
How often should I get this test?
Your doctor will determine frequency based on your symptoms or treatment plan. Follow-up tests may be needed if allergies, asthma, or other conditions are being managed.
Can diet or supplements affect IgE test results?
Dietary changes or supplements (like certain herbs or vitamins) can sometimes influence immune responses, but they rarely directly alter IgE levels. Always discuss with your doctor before making major dietary changes.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy