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Immunoglobulin A (IgA) in Serum or Plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of Immunoglobulin A (IgA), a type of antibody in your blood. IgA helps protect your body against infections and is important for immune function.

Quick summary

["IgA levels help assess immune health and detect potential deficiencies or abnormalities."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
105984-9
Short code
IgA kappa Ser Ql IFE
Synonyms
IgA kappa Ser Ql IFE
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
immunofixation
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Might You Need This Test?

Your healthcare provider may order an IgA test if you have symptoms like frequent infections, immune system issues, or if they suspect conditions like IgA deficiency, autoimmune diseases, or certain types of allergies. It may also be part of a routine check-up or to monitor a known condition.

What Does the Test Involve?

A small blood sample is taken from a vein in your arm. The blood is then sent to a lab for analysis. The test measures the concentration of IgA in your serum or plasma.

What Are Common Uses?

IgA tests are often used to diagnose or monitor conditions affecting the immune system, such as IgA deficiency, certain autoimmune diseases, or to check for immune responses in people with chronic illnesses.

What Are Possible Results?

Results can vary based on individual health, age, and other factors. While specific reference ranges may differ by lab, low IgA levels may indicate immune deficiencies, while very high levels could suggest certain immune disorders or conditions like multiple myeloma.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

IgA plays a critical role in protecting mucosal surfaces (like the respiratory and digestive tracts) from infections. Low IgA levels can increase susceptibility to infections and may require further evaluation for conditions like primary immunodeficiency. High IgA levels can sometimes be associated with autoimmune diseases or other systemic conditions and should be discussed with your healthcare provider.

Short name

IgA Level

Frequently asked questions

How is IgA Test Different from Other Antibody Tests?
Unlike tests for other immunoglobulins (like IgG or IgM), IgA specifically measures the antibody that primarily targets infections at body surfaces. It is often used to evaluate immune function in areas like the gut, lungs, and sinuses.
What Does It Mean If My IgA Level Is Low?
A low IgA level may suggest an immune deficiency, which can make you more prone to infections. Your doctor may recommend further testing or treatments to address potential deficiencies or underlying conditions.
Can Diet or Supplements Affect IgA Levels?
Dietary factors, such as certain foods or supplements, can sometimes influence immune function indirectly, but they do not directly affect IgA levels. Always follow your doctor’s advice regarding dietary changes or supplements.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy