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Immunoglobulin A (IgA) in serum/plasma by nephelometry

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of Immunoglobulin A (IgA), a type of antibody in your blood. IgA helps protect your body from infections by fighting bacteria and viruses.

Quick summary

["IgA helps defend your immune system and may be checked if you have recurring infections or certain immune-related conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
74865-7
Short code
IgA lamba SerPl-mCnc
Synonyms
IgA lamba SerPl-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

IgA is one of the key proteins in your immune system. It’s found in high concentrations in bodily fluids like saliva, tears, and mucus, but it’s also present in your blood. This test specifically looks at the concentration of IgA in your serum or plasma, which can help doctors understand how well your immune system is functioning to fight infections.

Why Might You Need This Test?

Doctors may order an IgA test if you have symptoms like frequent infections, digestive issues, or if you’re being evaluated for conditions like common variable immunodeficiency (CVID), certain autoimmune diseases, or after receiving certain treatments that affect the immune system.

What to Expect Before the Test

No special preparation is usually needed for this test. You may have a small needle inserted into your arm to draw blood. If you’re taking blood from a vein in your arm, you might feel a slight pinch or pressure, but it’s generally quick and not painful. If you’re concerned about needles, let your healthcare provider know.

What to Expect During the Test

The blood sample is collected and sent to a lab where it’s analyzed using a method called nephelometry. This technique measures how much light scatters when it interacts with IgA particles in the blood. The results help determine your IgA levels.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Low IgA levels may indicate a weakened immune response, increasing your risk of infections. High IgA levels can sometimes be linked to certain autoimmune conditions or allergic reactions. Your doctor will use these results along with your medical history and symptoms to guide diagnosis and treatment.

Short name

IgA Level

Frequently asked questions

Why might my IgA levels be checked if I have frequent infections?
If you frequently get infections, especially in areas like the sinuses, lungs, or digestive tract, your IgA levels might be low. This could suggest an underlying immune deficiency, such as common variable immunodeficiency (CVID), where your body doesn’t produce enough antibodies to fight infections effectively.
What could cause my IgA levels to be higher than normal?
Elevated IgA levels can sometimes be associated with autoimmune diseases, such as lupus or certain inflammatory conditions. They may also appear in people with allergies or after certain infections. Your doctor will review your symptoms and medical history to determine the best course of action.
Is there anything I should avoid before this test?
No specific preparations are needed for this test, but if you’re on blood-thinning medications or have a history of bleeding disorders, let your healthcare provider know before the test. Avoiding alcohol or certain medications that might affect your immune system can also help ensure accurate results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy