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Immunoglobulin A (IgA) by latex agglutination (screening test)

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of Immunoglobulin A (IgA), a type of antibody in your blood. IgA helps protect your body from infections.

Quick summary

["IgA helps fight infections and supports immune function; low levels may indicate immune system issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
105985-6
Short code
IgA lamba Ser Ql IFE
Synonyms
IgA lamba Ser Ql IFE
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
immunofixation
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

IgA is one of the key proteins in your immune system. It helps protect your body from harmful bacteria and viruses by binding to them. This test screens for IgA levels in your blood, which can help identify potential immune deficiencies or conditions like common variable immunodeficiency (CVID).

Why Might You Need This Test?

Your healthcare provider may order this test if you have symptoms like frequent infections, recurrent sinus or lung infections, or if you have a history of immune-related conditions. It may also be used as part of a broader evaluation for certain autoimmune diseases or to monitor immune function in certain treatments.

What to Expect Before the Test

No special preparation is usually needed for this test. You may have a small needle inserted into your arm to draw blood. If you are on blood thinners or have a history of bleeding issues, let your provider know beforehand.

What to Expect During the Test

The blood sample is collected and processed to detect IgA antibodies. The test uses a latex agglutination method, which involves mixing blood with latex particles coated with IgA antibodies. If IgA is present, the particles clump together, indicating a positive result.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Low IgA levels may suggest an immune deficiency, such as selective IgA deficiency, which can increase susceptibility to infections. High IgA levels might be seen in certain autoimmune conditions or chronic infections. This test is often used as a screening tool and may be followed by more specific tests if abnormalities are detected.

Short name

IgA screening

Frequently asked questions

What Are Normal IgA Levels?
There are no specific numeric reference ranges provided here since they can vary by lab. Your results will be compared to your lab’s standards, and your healthcare provider will interpret them in the context of your overall health and symptoms.
What Does a Low IgA Level Mean?
A low IgA level may indicate an immune system issue that could make you more prone to infections. Your doctor may recommend further testing or treatment to address this. Symptoms like frequent colds, ear infections, or sinus issues may also prompt further evaluation.
What Does a High IgA Level Mean?
High IgA levels can sometimes be associated with autoimmune diseases, chronic infections, or certain inflammatory conditions. Your healthcare provider will discuss the results with you and may suggest additional tests or treatments based on your overall health and symptoms.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy