Insulin-like Growth Factor Binding Protein 1 (IGFBP1) Mass Concentration in Serum/Plasma
This test measures the amount of IGFBP1, a protein that helps regulate how insulin-like growth factors interact with cells in your body. It may be used to assess metabolic health or endocrine function.
["IGFBP1 levels can provide insights into how your body processes growth factors and may help identify certain metabolic or hormonal imbalances."]
Key facts at a glance
- LOINC
- 54216-7
- Short code
- IGF BP1 pre/p chal SerPl-mCnc
- Synonyms
- IGF BP1 pre/p chal SerPl-mCnc
- Category
- hormone
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Does This Test Measure?
IGFBP1 (Insulin-like Growth Factor Binding Protein 1) is a protein that binds to growth factors like IGF-1 and IGF-2, helping control their availability and activity in your body. This test quantifies its concentration in your blood, typically measured in serum or plasma.
Why Might You Need This Test?
Your healthcare provider may order this test if you have symptoms or conditions linked to abnormal IGFBP1 levels, such as metabolic disorders, growth abnormalities, or endocrine issues. It may also be part of broader evaluations for diabetes, liver disease, or hormonal imbalances.
How Is the Test Performed?
A blood sample is drawn from a vein, usually in your arm. The blood is then processed to separate serum or plasma for testing. The lab uses a specialized immunoassay or similar method to measure IGFBP1 concentration accurately.
What Are Possible Results?
Results are expressed as a mass concentration (e.g., micrograms per milliliter). While reference ranges vary by lab, they help compare your levels to what’s considered typical for healthy individuals.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance: IGFBP1 plays a role in regulating growth factor signaling, which influences metabolism, cell growth, and tissue repair. Elevated or low levels may indicate conditions like insulin resistance, liver disease, or hormonal disorders. Always discuss results with your healthcare provider, as they’ll interpret them in the context of your overall health and symptoms.
Short name
IGFBP1 Level
Frequently asked questions
What does a high IGFBP1 level mean?
What does a low IGFBP1 level mean?
Is this test commonly used for routine check-ups?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy