Insulin-like Growth Factor Binding Protein 1 (IGFBP1) Concentration
This test measures the level of IGFBP1, a protein that helps regulate how insulin-like growth factors interact with cells. It may be used to assess hormone balance, especially in conditions affecting growth or metabolism.
["IGFBP1 helps control how growth factors work in your body and may be checked if you have concerns about growth issues, metabolic disorders, or hormonal imbalances."]
Key facts at a glance
- LOINC
- 69945-4
- Short code
- IGF BP1 Vag Ql
- Synonyms
- IGF BP1 Vag Ql
- Category
- hormone
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why Might This Test Be Ordered?
Your healthcare provider may order this test if you have symptoms or conditions linked to abnormal IGFBP1 levels, such as growth problems in children, metabolic disorders, or certain hormonal imbalances. It could also be part of a broader evaluation for conditions like acromegaly, hypopituitarism, or liver disease.
What Does This Test Measure?
IGFBP1 is a protein produced by cells that binds to insulin-like growth factors (IGFs), preventing them from activating certain receptors. By measuring IGFBP1, doctors can better understand how these growth factors are being regulated in your body.
Sample Collection and Preparation
Blood is drawn from a vein in your arm, usually in a clinic or lab setting. The blood sample is then processed to separate serum or plasma, which is sent to the lab for testing. You may be asked to fast for a certain period before the test, depending on your provider’s instructions.
What to Expect Before the Test
There are no strict dietary restrictions for this test, but your provider may advise you to avoid certain medications or supplements that could affect results. If you’re pregnant or breastfeeding, always confirm with your doctor before having this test.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Elevated IGFBP1 levels may be associated with conditions like liver disease or certain metabolic disorders, while low levels could suggest issues with growth hormone regulation or other hormonal imbalances. However, interpretation depends on clinical context, including your symptoms and medical history.
Short name
IGFBP1 Serum/Plasma
Frequently asked questions
What causes IGFBP1 levels to change?
How long does it take to get results?
Can lifestyle or diet affect IGFBP1 levels?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy