Insulin-like Growth Factor Binding Protein 3 (IGFBP3) – Serum/plasma concentration

Why This Test Might Be Ordered

Your doctor may order this test if they suspect conditions affecting growth, metabolism, or hormone function. Common reasons include evaluating symptoms like slow wound healing, bone pain, or unexplained growth issues in children/adolescents. Adults might have it checked for metabolic disorders, such as diabetes or thyroid problems, or to monitor treatment responses.

What to Expect Before the Test

No special preparation is needed. You may have a blood sample drawn from a vein in your arm. If you’re taking certain medications (e.g., steroids), let your doctor know, as they could affect results.

What the Results Mean

Results are not typically provided as a single reference range since IGFBP3 levels vary by age, health status, and other factors. Your doctor will compare your results to your own baseline or clinical context to interpret them.

Common Conditions Linked to IGFBP3 Levels

Abnormal IGFBP3 levels may signal conditions like growth hormone deficiencies, metabolic disorders (e.g., insulin resistance), or bone-related issues (e.g., osteoporosis). In children, low levels might indicate growth hormone imbalance, while high levels could relate to metabolic syndrome or other endocrine disorders.