Insulin-like Growth Factor Binding Protein 3 (IGFBP3) – Serum Concentration
This test measures the amount of IGFBP3, a protein that helps regulate how insulin-like growth factors work in your body. It may be checked to assess growth hormone function, metabolic health, or potential hormone-related conditions.
["IGFBP3 helps balance growth and metabolism; abnormal levels may signal underlying health concerns."]
Key facts at a glance
- LOINC
- 59997-7
- Short code
- IGF BP3 sp7 p chal SerPl-mCnc
- Synonyms
- IGF BP3 sp7 p chal SerPl-mCnc
- Category
- hormone
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may recommend this test if you have symptoms or conditions linked to growth hormone imbalances, such as growth issues in children, metabolic disorders, or suspected pituitary problems. It may also be part of evaluations for conditions like acromegaly, hypopituitarism, or metabolic syndrome.
What to Expect Before the Test
No special preparation is needed for this blood test. You may have fasting instructions depending on your provider’s instructions, but typically, you can eat and drink normally unless advised otherwise. Bring any medications or supplements you’re taking to your appointment.
What to Expect During the Test
A healthcare professional will draw blood from a vein in your arm. You may feel a slight pinch, but the process is quick and usually not painful. You can resume normal activities immediately afterward.
What the Results Mean
Results are interpreted based on your overall health, symptoms, and medical history. Elevated levels may suggest certain metabolic or hormonal conditions, while low levels could indicate growth hormone deficiency or other issues. Your provider will discuss findings with you in the context of your care plan.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
IGFBP3 Level
Frequently asked questions
What does an abnormal IGFBP3 result mean?
How often should I get this test?
Can lifestyle changes affect IGFBP3 levels?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy