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Immunoglobulin G (IgG) Subclass 1, Serum or Plasma Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of Immunoglobulin G (IgG) subclass 1, a type of antibody in your blood. IgG is the most common antibody and helps protect your body from infections.

Quick summary

["IgG1 antibodies play a key role in fighting bacterial and viral infections."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
56618-2
Short code
IGF-I 10M p chal SerPl-mCnc
Synonyms
IGF-I 10M p chal SerPl-mCnc
Category
hormone
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

IgG1 is one of five subclasses of Immunoglobulin G (IgG), a type of protein in your blood that helps fight infections. This test specifically looks at the concentration of IgG1 antibodies, which are important for long-term immunity. IgG1 antibodies are particularly effective against bacteria and some viruses. Changes in IgG1 levels can sometimes indicate immune system function or response to treatments.

Why Might You Need This Test?

Your healthcare provider may order this test if they suspect an immune system disorder, such as a condition affecting antibody production. It could also be used to monitor treatment responses in conditions like autoimmune diseases or infections.

How Is the Test Performed?

A blood sample is taken from a vein, usually in your arm. The blood is then processed to separate the serum or plasma, where the IgG1 antibodies are measured using a specialized laboratory technique.

What Are Possible Results?

Results are typically reported as a mass concentration in grams per liter (g/L) or milligrams per deciliter (mg/dL). These values help determine if your IgG1 levels are within the expected range for your age and health status.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: IgG1 Levels and Health

Short name

IgG1 Subclass Test

Frequently asked questions

What Are Common Causes of Abnormal Results?
IgG1 levels can be affected by various conditions, including chronic infections, autoimmune diseases, or certain medications. Low IgG1 levels might suggest an immune deficiency, while high levels could be seen in certain infections or inflammatory conditions. Always discuss any changes in your test results with your healthcare provider.
How Often Should I Get This Test?
The frequency of this test depends on your medical condition and treatment plan. Your healthcare provider will determine how often you need retesting based on your specific needs and symptoms.
Can I Prepare for This Test?
No special preparation is usually needed for this blood test. However, you may be asked to fast for a few hours before the test if instructed by your healthcare provider.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy