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Fibrinogen, Serum/Plasma Mass Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of fibrinogen, a protein in your blood that helps with blood clotting.

Quick summary

["Fibrinogen helps your blood clot properly and supports wound healing."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
49850-1
Short code
IGF-I BS SerPl-mCnc
Synonyms
IGF-I BS SerPl-mCnc
Category
hormone
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Might This Test Be Done?

Your doctor may order this test to check for bleeding disorders, clotting problems, or to monitor conditions like liver disease, where fibrinogen production can be affected. It may also be used during pregnancy to assess risks of bleeding complications or after surgery to evaluate clotting function.

What to Expect Before the Test

No special preparation is needed. You may have a small needle inserted into your arm or hand to draw blood. If you’re taking blood from a vein, you might feel a slight pinch or discomfort, but it usually lasts only a few seconds. If you’re concerned about needles, let your healthcare provider know.

What Happens During the Test?

Blood is collected in a tube and sent to a lab for analysis. The test measures the protein fibrinogen in your blood plasma or serum. Results are typically ready within a few days.

What the Results Mean

Results are compared to a general reference range, but exact values can vary by lab. Low levels may suggest bleeding disorders or liver issues, while very high levels could indicate conditions like severe inflammation or pregnancy-related changes. Your doctor will discuss your specific results with you.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Low fibrinogen levels can indicate conditions like liver disease, severe infections, or certain blood disorders that impair clotting. High levels may be seen in pregnancy, severe inflammation, or after blood loss. Monitoring fibrinogen helps guide treatment for bleeding risks or clotting support.

Short name

Fibrinogen Level

Frequently asked questions

How long does it take to get my results?
Results are usually available within a few days to a week, depending on your lab’s processing time. Your doctor will contact you once they’re ready to discuss them.
Can I eat or drink before this test?
You can eat and drink normally before this test, as no special diet or fasting is required.
Is there anything I should avoid before the test?
Avoid heavy exercise or strenuous activity 24 hours before the test, as it may affect your blood clotting levels. Let your doctor know if you’re on any medications that could influence results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy