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Insulin-like Growth Factor Binding Protein 2 (IGFBP-2) Serum/Plasma Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of IGFBP-2, a protein that helps regulate how insulin-like growth factors affect cells in your body.

Quick summary

["IGFBP-2 helps balance growth signals in your body and may be checked if you have concerns about growth disorders or metabolic health."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
60011-4
Short code
IGF-I sp2 p chal SerPl-mCnc
Synonyms
IGF-I sp2 p chal SerPl-mCnc
Category
hormone
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms or conditions linked to abnormal IGFBP-2 levels, such as growth issues in children, metabolic disorders, or certain cancers. It may also be part of monitoring for conditions like diabetes, liver disease, or kidney problems.

What to Expect Before the Test

No special preparation is usually needed. You may fast for 8–12 hours before the test if instructed, but always follow your provider’s specific instructions. Bring any medications you’re taking to your appointment.

How the Test Is Performed

A blood sample is drawn from a vein in your arm by a healthcare professional. The blood is then processed to measure IGFBP-2 levels in your serum or plasma.

What the Results Mean

Results are interpreted by your healthcare provider based on your medical history, symptoms, and other test results. Elevated or low levels may signal potential health concerns that need further evaluation.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

IGFBP-2

Frequently asked questions

What causes IGFBP-2 levels to change?
IGFBP-2 levels can be influenced by factors like liver or kidney disease, certain medications, hormonal imbalances, or metabolic conditions such as diabetes. Stress, diet, and genetics may also play a role.
How long will it take to get my results?
Results are typically available within 1–3 business days, depending on your lab and healthcare provider. Follow-up instructions will be provided by your provider.
Can I take anything before or after the test?
Avoid smoking or consuming alcohol for 24 hours before the test. If you’re on medications, check with your provider to see if you should pause them temporarily. Do not eat or drink anything (except water) for 8–12 hours before fasting if instructed.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy