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Insulin-like Growth Factor Binding Protein 7 (IGFBP-7) Serum Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of IGFBP-7, a protein that binds to insulin-like growth factors in your blood. It may be used to assess certain metabolic or endocrine conditions.

Quick summary

["IGFBP-7 helps regulate growth and metabolism; abnormal levels may signal underlying health concerns."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
60006-4
Short code
IGF-I sp7 p chal SerPl-mCnc
Synonyms
IGF-I sp7 p chal SerPl-mCnc
Category
hormone
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is IGFBP-7?

IGFBP-7 (Insulin-like Growth Factor Binding Protein 7) is a protein that plays a role in transporting and regulating insulin-like growth factors in your body. These factors are important for cell growth and development. Your doctor may order this test if they suspect conditions affecting growth, metabolism, or bone health.

Why Might This Test Be Ordered?

A healthcare provider might recommend this test if you have symptoms or risk factors linked to metabolic disorders, such as growth abnormalities, bone density issues, or certain endocrine conditions. It may also be used in research or specialized clinical settings.

What Does the Test Involve?

A blood sample is drawn from a vein, typically in your arm. The sample is sent to a lab for analysis using a specialized immunoassay method to measure IGFBP-7 concentration.

What Are Common Results and Next Steps?

Results are reported as a concentration value (e.g., micrograms per milliliter). Your results will be reviewed by a healthcare provider to interpret their meaning in your specific situation. Follow-up may include additional tests, lifestyle advice, or treatment recommendations based on findings.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: IGFBP-7’s Role in Health

Short name

IGFBP-7

Frequently asked questions

How does IGFBP-7 relate to common health conditions?
While IGFBP-7 itself is not as widely studied for common conditions as other growth factors, elevated or low levels may be associated with metabolic disorders, bone metabolism issues, or certain growth-related syndromes. Your doctor will consider clinical context when evaluating results.
What if my test results are outside of typical ranges?
If your IGFBP-7 levels are abnormal, your healthcare provider will discuss potential causes with you, which may include genetic factors, metabolic disorders, or other underlying health conditions. They may recommend further testing or adjustments to your care plan.
Can lifestyle changes affect IGFBP-7 levels?
While diet, exercise, and overall health can influence related growth factors and metabolic processes, IGFBP-7 levels are primarily influenced by genetic and hormonal factors. Your doctor may suggest lifestyle modifications if they are part of a broader treatment plan for a related condition.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy