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Insulin-like Growth Factor 1 (IGF-1) Serum Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of IGF-1, a hormone produced by the liver that plays a key role in growth, development, and metabolism. It helps assess how well your body is responding to growth hormone.

Quick summary

["IGF-1 helps track growth hormone function and potential growth or metabolic disorders."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
73561-3
Short code
IGF-I Z-score SerPl
Synonyms
IGF-I Z-score SerPl
Category
hormone
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Might You Need This Test?

Your doctor may order an IGF-1 test if you have symptoms like slow growth in children, abnormal bone development, or metabolic issues. It’s also used to monitor conditions like growth hormone deficiency, acromegaly, or Turner syndrome.

What to Expect During the Test

A blood sample is taken from a vein, usually in your arm. You may feel a small pinch, but it’s quick. No special preparation is needed unless instructed otherwise.

How the Results Are Used

Results help doctors diagnose or manage conditions affecting growth, metabolism, or hormone levels. They’re often compared to age-appropriate reference ranges for children or adults.

Common Conditions Monitored

IGF-1 is monitored in conditions like growth hormone deficiency (in children/adults), acromegaly (excess growth hormone), or Turner syndrome. It may also be checked in research or clinical trials exploring growth-related treatments.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: IGF-1’s Role in Health

Short name

IGF-1 Level

Frequently asked questions

How does IGF-1 differ from my baseline test results?
IGF-1 results are compared to reference ranges based on age and sex. A doctor will interpret your results in the context of your medical history, symptoms, and other tests. For example, very low levels may suggest growth hormone deficiency, while very high levels could indicate acromegaly or other metabolic issues.
What do abnormal IGF-1 results mean?
Abnormal results may signal an underlying condition requiring further evaluation, such as testing for growth hormone levels or imaging studies. Your doctor will guide next steps based on your specific situation.
Can lifestyle changes affect IGF-1 levels?
Yes, factors like nutrition, exercise, and weight can influence IGF-1. Maintaining a balanced diet, staying physically active, and managing chronic conditions (e.g., diabetes) may support healthy hormone levels, but results depend on individual health and medical needs.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy