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Insulin-like Growth Factor 1 (IGF-1) with Serum/Plasma Concentration Measurement

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of IGF-1, a hormone produced by the liver in response to growth hormone from the pituitary gland, which plays a key role in growth and development.

Quick summary

["IGF-1 helps regulate growth, metabolism, and cell repair—important for children’s growth and adults’ overall health."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
25759-2
Short code
IGF sp11 p chal SerPl-sCnc
Synonyms
IGF sp11 p chal SerPl-sCnc
Category
hormone
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why IGF-1 Matters in Growth and Development

IGF-1 is crucial during childhood for bone and tissue growth. In adults, it supports muscle mass, bone density, and metabolism. Low levels may signal growth hormone deficiency or other conditions affecting growth or metabolism.

When This Test Is Ordered

Doctors may check IGF-1 levels if you have symptoms like slow growth in children, muscle weakness, or unexplained weight changes in adults. It’s also used to monitor conditions like growth hormone deficiency, Turner syndrome, or metabolic disorders.

What to Expect Before the Test

No special preparation is needed, but fasting may be required depending on the lab’s protocol. Bring any medications or supplements you’re taking to discuss with your provider.

What the Results Mean

Results help doctors compare your IGF-1 level to what’s typical for your age and health. They may also consider your medical history and other test results to diagnose or guide treatment.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: IGF-1’s Role in Health and Disease

Short name

IGF-1 Level

Frequently asked questions

How long does it take to get my IGF-1 results back?
Results are typically available within 1–3 business days, depending on your lab. Your doctor will discuss them with you during your follow-up visit.
Can IGF-1 levels change with diet or exercise?
Diet and exercise can influence IGF-1 indirectly—e.g., poor nutrition may lower it—but direct effects vary. Your doctor will consider lifestyle factors when interpreting results.
Is IGF-1 testing covered by insurance?
Coverage depends on your diagnosis or reason for testing. Check with your insurance provider or ask your doctor to confirm before the test.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy