Insulin-like Growth Factor Binding Protein 1 (IGFBP-1) Serum Concentration
This test measures the amount of IGFBP-1, a protein that helps regulate how insulin-like growth factors work in your body.
["IGFBP-1 helps balance growth signals in your body and may be checked if you have concerns about growth, metabolism, or certain hormonal conditions."]
Key facts at a glance
- LOINC
- 25760-0
- Short code
- IGF sp12 p chal SerPl-sCnc
- Synonyms
- IGF sp12 p chal SerPl-sCnc
- Category
- hormone
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may order this test if you have symptoms or conditions linked to abnormal growth hormone or IGFBP-1 levels, such as growth issues in children, metabolic disorders, or certain cancers. It may also be part of monitoring for conditions like liver disease or diabetes.
What to Expect Before the Test
No special preparation is typically needed, but you may be asked to fast for 8–12 hours before the test if it involves drawing blood from your vein. Wear comfortable clothing and let your healthcare provider know about any medications or health conditions you have.
What Happens During the Test
A healthcare professional will insert a small needle into a vein in your arm to draw a blood sample. You may feel a slight pinch, but it usually doesn’t cause discomfort. The blood is then sent to a lab for analysis.
What the Results Mean
Results are not provided with specific reference ranges, as they vary by lab and individual health. Your provider will interpret the results in relation to your symptoms, medical history, and other tests. Abnormal levels may suggest conditions affecting growth, metabolism, or hormone function.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
IGFBP-1 plays a role in regulating how insulin-like growth factors interact with cells, influencing growth, metabolism, and tissue repair. Low levels may be associated with liver disease, malnutrition, or certain cancers, while high levels could indicate conditions like diabetes or growth hormone resistance. Your provider will use the results to guide further evaluation or treatment.
Short name
IGFBP-1
Frequently asked questions
What does a normal or abnormal IGFBP-1 result mean?
How often should I get this test?
Can lifestyle changes affect IGFBP-1 levels?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy