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Insulin-like Growth Factor 1 (IGF-1) Serum Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of IGF-1, a hormone linked to growth and metabolism, in your blood serum. It helps assess growth hormone function and potential growth or metabolic disorders.

Quick summary

["IGF-1 levels can indicate whether your growth hormone is working as expected or if there may be underlying health concerns."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
57986-2
Short code
IGF sp1 p chal SerPl-mCnc
Synonyms
IGF sp1 p chal SerPl-mCnc
Category
hormone
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like slow growth in children, short stature, or metabolic issues. Adults might get it if they have concerns about growth hormone deficiency, metabolic disorders, or conditions affecting hormone balance.

What to Expect Before the Test

No special preparation is usually needed. You may fast for 8–12 hours before the test if instructed, but always follow your provider’s directions. Bring any medications or supplements you’re taking to discuss with them.

What Happens During the Test

A small blood sample will be drawn from a vein, typically in your arm. The process is quick and usually causes only minor discomfort. The sample is sent to a lab for analysis.

What the Results Mean

Results help determine if your IGF-1 levels are within expected ranges for your age and sex. Abnormal levels may signal conditions like growth hormone deficiency, acromegaly, or other metabolic disorders that require further evaluation.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

IGF-1 Level

Frequently asked questions

How might my IGF-1 levels affect my health?
Low IGF-1 levels may indicate growth hormone deficiency, which can slow growth in children or cause fatigue, weakness, or metabolic issues in adults. High levels could suggest overproduction of growth hormone, leading to conditions like acromegaly (enlarged hands/feet, organ enlargement). Always discuss results with your provider for personalized interpretation.
What if my results are outside the normal range?
If your results are abnormal, your provider may recommend additional tests, like growth hormone stimulation tests, or refer you to a specialist for further evaluation. They’ll work with you to determine the next steps based on your symptoms and medical history.
Do I need to do anything after the test?
You can resume your normal activities immediately. If you had fasting instructions, eat a regular meal afterward. Keep any follow-up appointments and discuss results with your healthcare provider to understand next steps.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy