Insulin-like Growth Factor Binding Protein 2 (IGFBP-2) Serum Concentration
This test measures the amount of IGFBP-2, a protein that helps regulate how insulin-like growth factors interact with cells.
["IGFBP-2 helps control growth and metabolism; levels may be checked in conditions affecting these processes."]
Key facts at a glance
- LOINC
- 25764-2
- Short code
- IGF sp2 p chal SerPl-sCnc
- Synonyms
- IGF sp2 p chal SerPl-sCnc
- Category
- hormone
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Does This Test Measure?
IGFBP-2 is a protein that binds to insulin-like growth factors (IGFs) in your blood. It plays a role in how these growth factors affect cells, particularly in tissues involved in growth, metabolism, and repair. Your doctor may order this test to assess how IGFs are being managed in your body, especially if you have concerns about growth disorders, metabolic conditions, or other health issues linked to IGF activity.
Why Might This Test Be Ordered?
A healthcare provider might recommend this test if you have symptoms or conditions such as growth problems in children, metabolic disorders, or certain types of cancer. It may also be used in research or monitoring settings where understanding IGFBP-2 levels is important.
Sample Collection and Preparation
This test requires a blood sample drawn from a vein in your arm. After collecting the blood, it is typically sent to a lab for processing. You may need to fast for a certain period before the test, depending on your doctor’s instructions.
What to Expect Before the Test
On the day of your test, avoid eating or drinking anything except water for a specified time (usually 8–12 hours). Wear comfortable clothing and plan to rest for a short time afterward, as you might feel lightheaded from the needle. Inform your doctor about any medications you’re taking or recent illnesses.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
IGFBP-2 levels can be elevated in conditions like liver disease, kidney disease, or certain cancers, where the body’s protein regulation may be disrupted. Lower levels might be seen in metabolic disorders or growth-related conditions. Your doctor will interpret results in the context of your overall health and symptoms.
Short name
IGFBP-2
Frequently asked questions
How Long Does It Take to Get Results?
What Are Normal Results?
Follow your doctor’s instructions strictly. Avoid eating or drinking anything except water for the fasting period before the test. Afterward, you can resume your normal diet and activities unless otherwise advised.
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy