Insulin-like Growth Factor Binding Protein 3 (IGFBP-3) Serum Concentration
This test measures the amount of IGFBP-3, a protein that helps regulate growth factors in your body. It can be part of evaluations for growth disorders, metabolic conditions, or hormonal imbalances.
["IGFBP-3 helps control growth and metabolism; low levels may signal underlying health concerns."]
Key facts at a glance
- LOINC
- 25765-9
- Short code
- IGF sp3 p chal SerPl-sCnc
- Synonyms
- IGF sp3 p chal SerPl-sCnc
- Category
- hormone
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may recommend this test if you have symptoms or conditions linked to abnormal growth factor regulation, such as growth hormone disorders, metabolic syndrome, or unexplained weight changes. It may also be used in research or monitoring certain chronic conditions.
What to Expect Before the Test
No special preparation is usually needed. You may be asked to fast for 8–12 hours before the test if instructed by your provider. Bring any medications you’re currently taking to your appointment.
How the Test Is Performed
A blood sample is drawn from a vein, typically in your arm, using a small needle. The sample is sent to a lab for analysis using an immunoassay method to measure IGFBP-3 concentration.
What the Results Mean
Results are compared to a reference range specific to your age, sex, and health status. While exact values can vary, very high or very low levels may indicate potential health concerns that need further evaluation.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
IGFBP-3
Frequently asked questions
IGFBP-3 plays a key role in transporting and regulating growth hormones in the body. Abnormal levels may be associated with conditions like acromegaly, growth hormone deficiency, or metabolic disorders. Your provider will discuss results in the context of your overall health.
How long will I need to wait for results?
Can I eat or drink anything before this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy