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IGFBP-7 (Insulin-Like Growth Factor Binding Protein 7) [Substance Concentration] in Serum or Plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of insulin-like growth factor binding protein 7 (IGFBP-7) in your blood. IGFBP-7 is a protein involved in cell growth, tissue repair, and regulation of the IGF signaling system.

Quick summary

["IGFBP-7 is a blood protein that helps regulate cell growth and is sometimes measured as a marker of tissue stress or kidney function."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
25769-1
Short code
IGF sp7 p chal SerPl-sCnc
Synonyms
IGF sp7 p chal SerPl-sCnc
Category
hormone
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is IGFBP-7?

IGFBP-7 is a protein that binds insulin-like growth factors and helps control how cells grow, divide, and respond to stress. It is produced by many tissues and can be measured in serum or plasma to give information about certain physiological and disease processes.

Why Might Your Doctor Order This Test?

Your healthcare provider may order an IGFBP-7 measurement as part of research or specialized evaluation of conditions involving cell stress, kidney injury, or growth regulation. It is not a routine screening test and is usually interpreted alongside other clinical findings and laboratory results.

How the Test Is Performed

A small sample of blood is drawn from a vein, usually in your arm, and sent to the laboratory. The laboratory measures the concentration of IGFBP-7 in the serum or plasma portion of your blood.

What the Results Mean

Results are reported as a concentration and should be interpreted by your healthcare provider in the context of your symptoms, medical history, and other tests. There is no single universal reference range that applies to everyone, and results can vary by laboratory method and population.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

IGFBP-7

Frequently asked questions

Is IGFBP-7 a routine blood test?
No. IGFBP-7 measurement is typically used in specialized or research settings rather than as a routine screening test. Your provider can explain whether it is appropriate for your situation.
Do I need to fast before this test?
Fasting requirements depend on the specific instructions from your healthcare provider and laboratory. Follow the preparation directions you are given.
Can I interpret my IGFBP-7 result on my own?
No. IGFBP-7 results must be interpreted by your healthcare provider together with your medical history, symptoms, and other test results, since levels can vary by method and clinical context.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy