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Serum/plasma Insulin-like Growth Factor Binding Protein 9 (IGFBP-9) Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of IGFBP-9, a protein that helps regulate growth factors in your body. It may be used to assess conditions affecting growth, metabolism, or vascular health.

Quick summary

["IGFBP-9 helps control how insulin-like growth factors work in your body."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
25771-7
Short code
IGF sp9 p chal SerPl-sCnc
Synonyms
IGF sp9 p chal SerPl-sCnc
Category
hormone
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Might This Test Be Ordered?

Your healthcare provider may order this test if you have symptoms or risk factors related to conditions like vascular diseases, metabolic disorders, or growth-related issues. It could also be part of a broader evaluation for suspected IGF-related disorders or monitoring treatment responses.

What Does This Test Measure?

IGFBP-9 is a protein that binds to insulin-like growth factors (IGFs) in your blood. Elevated or low levels may indicate imbalances in growth signaling pathways, which can affect tissue growth, blood vessel function, or metabolism.

Sample Collection and Preparation

This test requires a blood sample drawn from a vein in your arm. The blood is typically collected into a tube that separates serum or plasma from cells. The sample is then sent to a lab for analysis using a specialized immunoassay method.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the test if instructed by your provider. Avoid strenuous activity or consuming certain medications that could interfere with results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

IGFBP-9

Frequently asked questions

How long does it take to get results from this test?
Results are typically available within 1–3 business days, depending on your lab’s processing schedule. Your healthcare provider will discuss the results with you during your follow-up visit.
Can diet or medications affect IGFBP-9 levels?
Certain medications (e.g., steroids, growth hormone therapies) or dietary factors (e.g., protein intake) may influence IGFBP-9 levels. Always inform your provider about all medications or supplements you’re taking before testing.
Is fasting required for this test?
Fasting may not always be required, but your provider may specify dietary restrictions. Follow their instructions to ensure accurate results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy